By taking part in research you’ll be helping us to test and developed things like new models of care, support methods and drug treatments.

All of the studies you see below have been given approval by the Health Research Authority and will be carried out by experts with clinical, research and academic backgrounds.

Evaluating the Impact of Minimum Unit Pricing in Scotland on Harmful Drinkers

Who this study is aimed at?

Service users who are seeing treatment services in relation their alcohol use.

Who can’t take part?

Individuals with cognitive impairment or unable to understand and speak English.

Study summary

One off interview with a researcher.

Study visits

One.

Services taking part

Sheffield Treatment and Recovery Team.

Who to contact

Dr Olawale Lagundoye

How to contact

olawale.lagundoye@shsc.nhs.uk

ADAM: Alcohol Dependence and Adherence to Medicine

Who this study is aimed at?

Service users who have been diagnosed with alcohol dependence and are starting or recently started (within the past month) taking acamprosate to help stay off alcohol.

Who can’t take part?

Service users who are currently dependent on an illicit substance other than cannabis.

Study summary

Participants will be placed at random by a computer system in one of the three groups:

  • usual support
  • usual support and medication management
  • or usual support with medication management and a personal achievement award

Everyone taking part will receive the usual support from health workers while taking acamprosate, but those in the medication management and medication management with a personal achievement award groups will receive some additional support to take Acamprosate.

Study visits

One hour once every other month for 6 months with a researcher. Could also involve talking to a pharmacist on the phone regularly for 6 months.

Services taking part

Sheffield Treatment and Recovery Team.

Who to contact

Dr Ruta Rele.

How to contact

ruta.rele@shsc.nhs.uk

Find out more

You can find out more about the study by clicking here

IPS-AD Trial - Individual and Placement Support for Alcohol and Drug dependence

Who this study is aimed at?

Service users who have alcohol or drug dependency and are not working but would like support to find a job.

Who can’t take part?

Service users who are not interested in returning to paid employment, currently receiving detoxification treatment for drug or alcohol withdrawal, current legal proceedings which are likely to result in imprisonment.

Study summary

Participants will be randomised to either usual employment services support or will receive employment support from a Job Specialist.  The Job Specialist will help to create an individual job plan and meet the regularly to review it.

Study visits

Meetings with a Job Specialist and questionnaires, for up to 18 months.

Services taking part

Sheffield Treatment and Recovery Team.

Who to contact

Joanna Yardley

How to contact

Joanna.yardley@shsc.nhs.uk

The Adult Autism Spectrum Cohort – UK

Who this study is aimed at?

Adults aged 16 or older with a diagnosis of ASD.

Who can’t take part?

People who do not have a confirmed diagnosis of ASD.

Study summary

Questionnaire for people to be included in a cohort so that researchers can learn about the lives of adults on the autism spectrum.

Study visits

One off questionnaire. Participants may be contacted in the future to be asked if they would like to take part in autism-related studies.

Services taking part

Sheffield Adult Autism and Neurodevelopmental Service (SAANS)

Find out more

To find out more about the study click here

Lifestyle Health and Wellbeing Survey

Who this study is aimed at?

Adults who have severe mental ill health

Who can’t take part?

Adults who have not been diagnosed with a severe mental health condition.

Study summary

Questionnaire for participants to be included in a cohort so that researchers can learn about their health and wellbeing.

Study visits

One off questionnaire. Participants may be contacted in the future to be asked if they would like to take part in related studies.

Services taking part

Inpatient wards at the Longley Centre and Michael Carlisle Centre.

Who to contact

Alex Carey or Pete Stewart.

How to contact

Alex.carey@shsc.nhs.uk or pete.stewart@shsc.nhs.uk

COPe-support online resource for carers

Who this study is aimed at?

Families and friends (parents, partners, siblings, other relatives or close friends) of individuals affected by psychosis.

Who can’t take part?

Carers of people who have a mental illness other than psychosis.  More than one carer who might share the caring for the same individual.

Study summary

Carers will be randomised to either COPe-support or a non-interactive information website.

Study visits

Online questionnaires at 4 time-points over 8 months.  Option to take part in an interview at the end of the study.

Services taking part

Recovery Service North, Recovery Service South, Early Intervention in Psychosis Service and all mental health inpatient wards.

Who to contact

Laura Di Bona or Alex Carey.

How to contact

laura.dibona@shsc.nhs.uk or alex.carey@shsc.nhs.uk

Find out more

To find out more about the study click here

TIME: Take home naloxone Intervention Multi centre Emergency setting feasibility trial

Who this study is aimed at?

People who take opioid drugs such as heroin, morphine, fentanyl and methadone, and people who are friends or family members of a person at risk of opioid overdose.

Who can’t take part?

Drug service users (or friends and family members of service users) who have no experience of opioid misuse.

Study summary

One off interview lasting about 30-45 minutes or one off focus group lasting about 60 minutes.

Study visits

One.

Services taking part

Opiates Service. 

Who to contact

Zoe Black.

How to contact

zoe.black@shsc.nhs.uk

Complete smokefree policies in mental health inpatient settings: exploring the impact on smoking behaviour and the role of electronic cigarettes

Who this study is aimed at?

Tobacco smokers receiving inpatient treatment.

Who can’t take part?

People who have not said they are a tobacco smoker at admission to the ward.

Study summary

20-30 minute interview on the ward about smoking and about experience of being on a smokefree ward. Two further interviews taking 10-20 minutes after discharge, the first time just after discharge and the second time one month after.

Study visits

Three.

Services taking part

Inpatient wards at the Longley Centre and Michael Carlisle Centre.

Who to contact

Pete Stewart

How to contact

pete.stewart@shsc.nhs.uk

Smoking Cessation Intervention for Severe Mental Ill Health Trial (SCIMITAR)

Who this study is aimed at?

People who have taken part in the original SCIMITAR+ study and completed study questionnaires and gave carbon monoxide (CO) breath measures.

Who can’t take part?

People who did not take part, or complete the previous SCIMITAR study.

Study summary

Postal questionnaire and a meeting with a researcher to give a CO breath measure.

Study visits

One.

Services taking part

Various services and locations.

Who to contact

Dr Michelle Horspool.

How to contact

michelle.horspool@shsc.nhs.uk

SYMBAD: Study of Treatment for Agitation in People with Memory Problems

Who this study is aimed at?

People who have been diagnosed with dementia who are showing signs of agitation, e.g. aimless pacing, repetitive sentences and questions or aggression.

Who can’t take part?

People who are currently being treated with antidepressants or antipsychotics. Females under the age of 55 of childbearing potential.

Study summary

There is a wide choice of medicines available to treat symptoms of agitation, but it is not clear which treatments are best in those people who have dementia. This study lasts for 12 months and is divided into three parts:

  1. the consent and assessment part which will be completed in one or two visits,
  2. the treatment part (Mirtazipine or placebo) which takes 12 weeks and then
  3. final questionnaires at 6 and 12 months with the carer by telephone.

Study visits

Four visits and three telephone contacts with the person and their carer.

Services taking part

Older adult services at Edmund Road and the Longley Centre.

Who to contact

Dr Aparna Mordekar

How to contact

Aparna.mordekar@shsc.nhs.uk

TACK - Adapting and testing a technology supported and solution-focused intervention (DIALOG+) for people with chronic depression

Who this study is aimed at?

People who have symptoms of depression or non-psychotic low mood with a duration of illness of at least two years and are receiving treatment from an NHS mental health service with regular contact with clinicians.

Who can’t take part?

People who have a primary diagnosis of a substance misuse problem, a diagnosis of a mental disorder eg Alzheimer’s, current inpatients on a psychiatric ward. People who do not currently have clinical contact with a mental health professional.

Study summary

This research aims to develop a new approach to help people with chronic depression. Researchers have developed an intervention called “DIALOG+” which helped people with schizophrenia. DIALOG+ involved mental health staff using a tablet computer to ask about satisfaction with different areas of life and then working together to find solutions to concerns raised. After using DIALOG+, service users were more satisfied with life and had fewer symptoms. Service users and staff found the approach helpful and it saved the NHS money.

The second phase of the TACK programme is looking at the effectiveness of DIALOG+ for people with chronic depression on improving quality of life and clinical outcomes (such as depression symptoms). The intervention will be tested in routine meetings across six sites in England.  Researchers will also evaluate how cost-effective the intervention is within the NHS.  They will also determine what works well or not so well in order to improve training materials and resources for staff.

Study visits

Six months of monthly sessions, followed by six months of booster sessions, to be done at the same time as clinical appointments

Services taking part

Northlands Community Health Centre, Edmund Road and Eastglade Centre.

Who to contact

Dani Chadderton or Shonagh Scott.

How to contact

Danielle.chadderton@shsc.nhs.uk or shonagh.scott@shsc.nhs.uk

Find out more

To find out more about the study, click here

DLB Genetics - Detecting susceptibility genes for dementia with Lewy bodies

Who this study is aimed at?

  • People who have probable dementia with lewy bodies.
  • Two or more core clinical features without biomarkers or one clinical feature with biomarkers
  • A willingness to provide a blood or saliva sample for genetic analysis
  • White European ethnicity
  • People who have an available study partner

Who can’t take part?

  • People who do not have parkinsonism at mild and moderate stages of dementia.
  • Diagnosis of Parkinson disease dementia (PDD)
  • Diagnosis of substance misuse or substance dependence
  • Learning disability
  • Major psychiatric illness

Study summary

This study involves:

  • a trained research assistant or research nurse visiting you either at home or at a local clinic. This visit will last around two hours
  • answering questions about yourself and taking part in a memory test
  • providing a blood sample
  • inviting a family member or friend to help by answering some questions about your diagnosis.

Study visits

One visit of approximately two hours.

Services taking part

Older adult services at Edmund Road and the Longley Centre.

Who to contact

Dr Aparna Mordekar

How to contact

Aparna.mordekar@shsc.nhs.uk

Find out more

To find out more about this study, click here.

Evaluating Mental Health Decision Units in acute care pathways

Who this study is aimed at?

Service users who have recently had their first visit to the Decisions Unit.

Who can’t take part

Service users whose visit to the Decision Unit is not their first.

Study summary

This study involves answering six questions about quality of life when and again nine months later.  Researchers will also ask our professionals how much you have used services, and which services you have used for your mental health in the nine months before and after your first admission to the Decisions Unit.

There is also an option to take part in two in-depth interviews about your experiences of crisis care in mental health services. If so, the first interview will be within a fortnight of you leaving the Decisions Unit and the second interview will be nine months later.

Study visits

One to two. The second questionnaire can be completed by post, with an option for a further two visits if you choose to take part in the additional in-depth interviews.

Services taking part

Decisions Unit.

Who to contact

Dr Raihan Talukdar

How to contact

raihan.talukdar@shsc.nhs.uk

PPiP2: Prevalence of neuronal cell surface antibodies in patients with psychotic illness

Who this study is aimed at?

Service users aged 18-70 with symptoms of psychosis for longer than two weeks but less than two years.

Who can’t take part?

Service users who have had psychotic symptoms for longer than two years.

Study summary

Staff will collect a small sample of blood from you and other people with psychosis symptoms from across the country. They will also collect some information about your symptoms and background. If your blood test then shows that your immune system is not working properly they will discuss this with you. Researchers are exploring a possible treatment in a separate study called SINAPPS2 and you may be able to take part in this study.

Study visits

One visit of approximately 15 minutes.

Services taking part

Limbrick Health Centre

Who to contact

Dr Raihan Talukdar or Alex Carey.

How to contact

raihan.talukdar@shsc.nhs.uk or alex.carey@shsc.nhs.uk

Find out more

To find out more about this study, click here.

Mental health assessments and psychological therapy following self-harm

Who this study is aimed at?

People with personal experience of:

  • Self-harm (self-injury or self-poisioning with or without suicidal intent)
  • Mental health services and/or psychological therapies following self-harm (accessing and/or receiving)
  • Caring or supporting a person with self-harm

Who can’t take part?

People under the age of 18.

Study summary

Researchers are investigating what helps and does not help people receive mental health assessments and access psychological therapies after they present to hospital with self-harm.

Study visits

Completing one on-line survey lasting 20-40 minutes.

Services taking part

Liaison Service. 

Find out more

To find out more about this study, click here

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